Antibiotics : targets, mechanisms and resistance / edited by Claudio O Gualerzi, Letizia Brandi, Attilio Fabbretti, and Cynthia L Pon
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| | | | | Antibiotics : targets, mechanisms and resistance. - Weinheim , 2013. |
| | xxiv, 549 p. : ill. (some col.) ; 26 cm. | | A chemist's survey of different antibiotic classes -- Antibacterial discovery: problems and possibilities -- Impact of microbial natural products on antibacterial drug discovery -- Antibiotics and resistance: a fatal attraction -- Fitness costs of antibiotic resistance -- Inhibitors of cell-wall synthesis -- Inhibitors of bacetrial cell partitioning -- The membrane as a novel target site for antibiotics to kill persisting bacterial pathogens -- Bacterial membrane, a key for controlling drug influx and efflux -- Interference with bacterial cell-to-cell chemical signaling in development of new anti-infectives -- Recent developments in inhibitors of bacterial type IIA topoisomerases -- Antibiotics targeting bacterial RNA polymerase -- Inhibitors targeting riboswitches and ribozymes -- Targeting ribonuclease P -- Involvement of ribosome biogenesis in antibiotic functions, acquired resistance, and future opportunities in drug discovery -- Aminoacyl-tRNA synthetase inhibitors -- Antibiotics targeting translation initiation in prokaryotes -- Inhibitors of bacterial elongation factor EF-Tu -- Aminoglycoside antibiotics: structural decoding of inhibitors targeting the ribosomal decoding A site -- Reptidyltransferase inhibitors of the bacterial ribosome -- Antibiotics inhibiting the translocation step of protein elongation on the ribosome -- Antibiotics at the ribosomal exit tunnel--selected structual aspects -- Targeting HSP70 to fight cancer and bad bugs: one and the same battle? | | ISBN 9783527333059 (hbk.) | | .-ISBN 3527333053 (hbk.). | | | | 1. Drug Resistance, Bacterial - pharmacology 2. Anti-Bacterial Agents - pharmacology.I. Gualerzi, Claudio O. - 1942- II. Brandi, Letizia III. Fabbretti, Attilio IV. Pon, Cynthia L. - 1942- V. Title | | | Library : UiTM Shah Alam |
| | Accn No. | Item Status | Add Id | Location | SMD | Item Category | | 966099 | Shelf | | PTAR KAMPUS PUNCAK ALAM(PPA) | BOOK | RAK TERBUKA (OPEN SHELVES) |
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