Handbook of drug screening / edited by Ramakrishna Seethala, Prabhavathi B. Fernandes
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| | | | | Handbook of drug screening. |
| | xiii, 597 pages : illustrations ; 24 cm Drugs and the pharmaceutical sciences v. 114. | | Moving into the third millennium after a century of screening -- Basic considerations in designing high-throughput screening assays -- Screening platforms -- Homogeneous assays for high-throughput and ultrahigh-throughput screening -- Microbe-based screening systems -- Molecular genetic screen design for agricultural and pharmaceutical product discovery -- Receptor screens for small molecule agonist and antagonist discovery -- Functional assay screens -- Enzyme screens -- Screening strategies for ion channel targets -- High-throughput screening assays for detection of transcription -- Screening of combinatorial biology libraries for natural products discovery -- Higher-throughput screening assays with human hepatocytes for hepatotoxicity, metabolic stability, and drug-drug interaction potential -- High-throughput screening for metabolism-based drug-drug interactions -- The ATCG of drug discovery -- Genomics/functional proteomics for identification of new targets -- Bioinformatics: identification of novel targets and their characterization -- The evolution of laboratory automation -- Robotics and automation -- Assay miniaturization: developing technologies and assay formats -- Screening in the NanoWorld: single-molecule spectroscopy and miniaturized high-throughput screening. | | ISBN 9780824705626 | | .-ISBN 0824705629. | | | | 1. Drug Evaluation, Preclinical - methods.I. Seethala, Ramakrishna - 1947- II. Fernandes, P. B. III. Title IV. Series | | | Library : UiTM Shah Alam; UITM Pulau Pinang |
| | Accn No. | Item Status | Add Id | Location | SMD | Item Category | | 579809 | Reference | | PERP. PERUBATAN TAR KAMPUS SG. BULOH(PPSB) | BOOK | ruj |
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